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Glucose 6-phosphate dehydrogenase deficiency enhances germ cell apoptosis and causes defective embryogenesis in Caenorhabditis elegans

Glucose 6-phosphate dehydrogenase (G6PD) deficiency, known as favism, is classically manifested by hemolytic anemia in human. More recently, it has been shown that mild G6PD deficiency moderately affects cardiac function, whereas severe G6PD deficiency leads to embryonic lethality in mice. How G6PD...

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Detalles Bibliográficos
Autores principales: Yang, H-C, Chen, T-L, Wu, Y-H, Cheng, K-P, Lin, Y-H, Cheng, M-L, Ho, H-Y, Lo, S J, Chiu, D T-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674345/
https://www.ncbi.nlm.nih.gov/pubmed/23640458
http://dx.doi.org/10.1038/cddis.2013.132