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Glucose 6-phosphate dehydrogenase deficiency enhances germ cell apoptosis and causes defective embryogenesis in Caenorhabditis elegans
Glucose 6-phosphate dehydrogenase (G6PD) deficiency, known as favism, is classically manifested by hemolytic anemia in human. More recently, it has been shown that mild G6PD deficiency moderately affects cardiac function, whereas severe G6PD deficiency leads to embryonic lethality in mice. How G6PD...
Autores principales: | Yang, H-C, Chen, T-L, Wu, Y-H, Cheng, K-P, Lin, Y-H, Cheng, M-L, Ho, H-Y, Lo, S J, Chiu, D T-Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674345/ https://www.ncbi.nlm.nih.gov/pubmed/23640458 http://dx.doi.org/10.1038/cddis.2013.132 |
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