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Pyrvinium targets autophagy addiction to promote cancer cell death

Autophagy is a cellular catabolic process by which long-lived proteins and damaged organelles are degradated by lysosomes. Activation of autophagy is an important survival mechanism that protects cancer cells from various stresses, including anticancer agents. Recent studies indicate that pyrvinium...

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Detalles Bibliográficos
Autores principales: Deng, Longfei, Lei, Yunlong, Liu, Rui, Li, Jingyi, Yuan, Kefei, Li, Yi, Chen, Yi, Liu, Yi, Lu, You, Edwards III, Carl K, Huang, Canhua, Wei, Yuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674351/
https://www.ncbi.nlm.nih.gov/pubmed/23640456
http://dx.doi.org/10.1038/cddis.2013.142