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Yeast techniques for modeling drugs targeting Bcl-2 and caspase family members

Development of drugs targeting Bcl-2 relatives and caspases, for treating diseases including cancer and inflammatory disorders, often involves measuring interactions with recombinant target molecules, and/or monitoring cancer cell killing in vitro. Here, we present yeast-based methods for evaluating...

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Detalles Bibliográficos
Autores principales: Beaumont, T E, Shekhar, T M, Kaur, L, Pantaki-Eimany, D, Kvansakul, M, Hawkins, C J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674352/
https://www.ncbi.nlm.nih.gov/pubmed/23640461
http://dx.doi.org/10.1038/cddis.2013.143