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Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach

Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults. GBM cells are highly resistant to apoptosis induced by antitumor drugs and radiotherapy resulting in cancer progression. We assessed whether a systems medicine approach, analysing the ability of tumor cells to execut...

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Detalles Bibliográficos
Autores principales: Murphy, Á C, Weyhenmeyer, B, Schmid, J, Kilbride, S M, Rehm, M, Huber, H J, Senft, C, Weissenberger, J, Seifert, V, Dunst, M, Mittelbronn, M, Kögel, D, Prehn, J H M, Murphy, B M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674364/
https://www.ncbi.nlm.nih.gov/pubmed/23681224
http://dx.doi.org/10.1038/cddis.2013.157