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Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults. GBM cells are highly resistant to apoptosis induced by antitumor drugs and radiotherapy resulting in cancer progression. We assessed whether a systems medicine approach, analysing the ability of tumor cells to execut...
Autores principales: | Murphy, Á C, Weyhenmeyer, B, Schmid, J, Kilbride, S M, Rehm, M, Huber, H J, Senft, C, Weissenberger, J, Seifert, V, Dunst, M, Mittelbronn, M, Kögel, D, Prehn, J H M, Murphy, B M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674364/ https://www.ncbi.nlm.nih.gov/pubmed/23681224 http://dx.doi.org/10.1038/cddis.2013.157 |
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