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A critical role of toll-like receptor 4 (TLR4) and its' in vivo ligands in basal radio-resistance
Toll-like receptor-4 (TLR4) plays a critical role in innate and acquired immunity, but its role in radio-resistance is unknown. We used TLR4 knockout (KO,(−/−)) mice and gut commensal depletion methods, to test the influence of TLR4 and its' in vivo agonist on basal radio-resistance. We found t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674368/ https://www.ncbi.nlm.nih.gov/pubmed/23722538 http://dx.doi.org/10.1038/cddis.2013.161 |