Pitt–Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription

TCF4 (transcription factor 4; E2-2, ITF2) is a transcription factor that when haplo-insufficient causes Pitt–Hopkins Syndrome (PTHS), an autism-spectrum disorder that is associated with pervasive developmental delay and severe intellectual disability. The TCF4 gene is also a risk factor with highly...

Descripción completa

Detalles Bibliográficos
Autor principal: Sweatt, J David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674405/
https://www.ncbi.nlm.nih.gov/pubmed/23640545
http://dx.doi.org/10.1038/emm.2013.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674405/
https://www.ncbi.nlm.nih.gov/pubmed/23640545
http://dx.doi.org/10.1038/emm.2013.32

Ejemplares similares