B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic β-cells

Glucagon-like peptide-1 (GLP-1) is a potent glucoincretin hormone and an important agent for the treatment of type 2 diabetes. Here we demonstrate that B-cell translocation gene 2 (BTG2) is a crucial regulator in GLP-1-induced insulin gene expression and insulin secretion via upregulation of pancrea...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Seung-Lark, Kwon, Okyun, Kim, Sun-Gyun, Lee, In-Kyu, Kim, Yong Deuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674408/
https://www.ncbi.nlm.nih.gov/pubmed/23703573
http://dx.doi.org/10.1038/emm.2013.47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674408/
https://www.ncbi.nlm.nih.gov/pubmed/23703573
http://dx.doi.org/10.1038/emm.2013.47

Ejemplares similares