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Partition of Myc into Immobile vs. Mobile Complexes within Nuclei

Myc levels are highly regulated and usually low in vivo. Dimerized with Max, it regulates most expressed genes and so directly and indirectly controls most cellular processes. Intranuclear diffusion of a functional c-Myc-eGFP, expressed from its native locus in murine fibroblasts and 3T3 cells or by...

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Detalles Bibliográficos
Autores principales: Rosales, Tilman, Nie, Zuqin, Kapoor, Varun, Casellas, Rafael, Knutson, Jay R., Levens, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674427/
https://www.ncbi.nlm.nih.gov/pubmed/23739641
http://dx.doi.org/10.1038/srep01953