The prognostic impact of FLT3-ITD and NPM1 mutations in patients with relapsed acute myeloid leukemia and intermediate-risk cytogenetics

Internal tandem duplication of the fms-like tyrosine kinase-3 gene (FLT3-ITD) and nucleophosmin-1 (NPM1) mutations have prognostic importance in acute myeloid leukemia (AML) patients with intermediate-risk karyotype at diagnosis, but less is known about their utility to predict outcomes at relapse....

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Detalles Bibliográficos
Autores principales: How, J, Sykes, J, Minden, M D, Gupta, V, Yee, K W L, Schimmer, A D, Schuh, A C, Kamel-Reid, S, Brandwein, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674456/
https://www.ncbi.nlm.nih.gov/pubmed/23708641
http://dx.doi.org/10.1038/bcj.2013.14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674456/
https://www.ncbi.nlm.nih.gov/pubmed/23708641
http://dx.doi.org/10.1038/bcj.2013.14

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