Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

Recent evidence shows that lipid raft membrane domains modulate both cell survival and death. Here, we have found that the phosphatidylinositol-3-kinase (PI3K)/Akt signaling pathway is present in the lipid rafts of mantle cell lymphoma (MCL) cells, and this location seems to be critical for full act...

Descripción completa

Detalles Bibliográficos
Autores principales: Reis-Sobreiro, M, Roué, G, Moros, A, Gajate, C, de la Iglesia-Vicente, J, Colomer, D, Mollinedo, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674457/
https://www.ncbi.nlm.nih.gov/pubmed/23727661
http://dx.doi.org/10.1038/bcj.2013.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674457/
https://www.ncbi.nlm.nih.gov/pubmed/23727661
http://dx.doi.org/10.1038/bcj.2013.15

Ejemplares similares