Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

Recent evidence shows that lipid raft membrane domains modulate both cell survival and death. Here, we have found that the phosphatidylinositol-3-kinase (PI3K)/Akt signaling pathway is present in the lipid rafts of mantle cell lymphoma (MCL) cells, and this location seems to be critical for full act...

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Detalles Bibliográficos
Autores principales: Reis-Sobreiro, M, Roué, G, Moros, A, Gajate, C, de la Iglesia-Vicente, J, Colomer, D, Mollinedo, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674457/
https://www.ncbi.nlm.nih.gov/pubmed/23727661
http://dx.doi.org/10.1038/bcj.2013.15

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