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The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints

INTRODUCTION: The immunoreceptor tyrosine-based activation motif (ITAM) pathway provides osteoclast co-stimulatory signals and regulates proliferation, survival and differentiation of effector immune cells. In the osteoclast, the receptors Triggering Receptor Expressed on Myeloid cells 2 (TREM2) and...

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Detalles Bibliográficos
Autores principales: Crotti, Tania N, Dharmapatni, Anak ASSK, Alias, Ekram, Zannettino, Andrew CW, Smith, Malcolm D, Haynes, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674611/
https://www.ncbi.nlm.nih.gov/pubmed/23146195
http://dx.doi.org/10.1186/ar4088