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Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2

Regulatory T (T reg) cells control progression to autoimmune diabetes in the BDC2.5/NOD mouse model by reining in natural killer (NK) cells that infiltrate the pancreatic islets, inhibiting both their proliferation and production of diabetogenic interferon-γ. In this study, we have explored the mole...

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Detalles Bibliográficos
Autores principales: Sitrin, Jonathan, Ring, Aaron, Garcia, K. Christopher, Benoist, Christophe, Mathis, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674700/
https://www.ncbi.nlm.nih.gov/pubmed/23650440
http://dx.doi.org/10.1084/jem.20122248