Sivelestat Attenuates Myocardial Reperfusion Injury during Brief Low Flow Postischemic Infusion

The neutrophil elastase inhibitor sivelestat (ONO-5046) possesses unknown mechanisms of cardioprotection when infused following global ischemia, even in the absence of neutrophils. Since myocardial ischemia-reperfusion injury is strongly associated with endothelial dysfunction and reactive oxygen sp...

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Detalles Bibliográficos
Autores principales: Aune, Sverre E., Yeh, Steve T., Kuppusamy, Periannan, Kuppusamy, M. Lakshmi, Khan, Mahmood, Angelos, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674745/
https://www.ncbi.nlm.nih.gov/pubmed/23766850
http://dx.doi.org/10.1155/2013/279847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674745/
https://www.ncbi.nlm.nih.gov/pubmed/23766850
http://dx.doi.org/10.1155/2013/279847

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