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BAD overexpression inhibits cell growth and induces apoptosis via mitochondrial-dependent pathway in non-small cell lung cancer

BACKGROUND: The pro-apoptotic Bcl-2 protein BAD initiated apoptosis in human cells and has been identified as a prognostic marker in non-small cell lung cancer (NSCLC). In this study, we aimed to explore the functions of BAD in NSCLC. METHODS: Overexpression of BAD was performed by transfecting diff...

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Detalles Bibliográficos
Autores principales: Jiang, Li, Luo, Man, Liu, Dan, Chen, Bojiang, Zhang, Wen, Mai, Lin, Zeng, Jing, Huang, Na, Huang, Yi, Mo, Xianming, Li, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674892/
https://www.ncbi.nlm.nih.gov/pubmed/23725574
http://dx.doi.org/10.1186/1475-2867-13-53