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Activation of signaling receptors: do ligands bind to receptor monomer, dimer, or both?
A recent study by Dietz et al. using single-molecule fluorescence microscopy techniques demonstrates that, in the absence of the ligand InlB, the MET receptor exists as both a monomer and a dimer on the cell membrane, and addition of the ligand leads to increased MET dimerization. Under the crowded...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674895/ https://www.ncbi.nlm.nih.gov/pubmed/23731691 http://dx.doi.org/10.1186/2046-1682-6-7 |