Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans

BACKGROUND: One of the key genes that regulate human brain size, MCPH1 has evolved under strong Darwinian positive selection during the evolution of primates. During this evolution, the divergence of MCPH1 protein sequences among primates may have caused functional changes that contribute to brain e...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Li, Ming, Lin, Qiang, Qi, Xuebin, Su, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674976/
https://www.ncbi.nlm.nih.gov/pubmed/23697381
http://dx.doi.org/10.1186/1741-7007-11-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674976/
https://www.ncbi.nlm.nih.gov/pubmed/23697381
http://dx.doi.org/10.1186/1741-7007-11-62

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