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Scrutinizing MHC-I Binding Peptides and Their Limits of Variation

Designed peptides that bind to major histocompatibility protein I (MHC-I) allomorphs bear the promise of representing epitopes that stimulate a desired immune response. A rigorous bioinformatical exploration of sequence patterns hidden in peptides that bind to the mouse MHC-I allomorph H-2K(b) is pr...

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Detalles Bibliográficos
Autores principales: Koch, Christian P., Perna, Anna M., Pillong, Max, Todoroff, Nickolay K., Wrede, Paul, Folkers, Gerd, Hiss, Jan A., Schneider, Gisbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674988/
https://www.ncbi.nlm.nih.gov/pubmed/23754940
http://dx.doi.org/10.1371/journal.pcbi.1003088