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RSR-2, the Caenorhabditis elegans Ortholog of Human Spliceosomal Component SRm300/SRRM2, Regulates Development by Influencing the Transcriptional Machinery

Protein components of the spliceosome are highly conserved in eukaryotes and can influence several steps of the gene expression process. RSR-2, the Caenorhabditis elegans ortholog of the human spliceosomal protein SRm300/SRRM2, is essential for viability, in contrast to the yeast ortholog Cwc21p. We...

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Detalles Bibliográficos
Autores principales: Fontrodona, Laura, Porta-de-la-Riva, Montserrat, Morán, Tomás, Niu, Wei, Díaz, Mònica, Aristizábal-Corrales, David, Villanueva, Alberto, Schwartz, Simó, Reinke, Valerie, Cerón, Julián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675011/
https://www.ncbi.nlm.nih.gov/pubmed/23754964
http://dx.doi.org/10.1371/journal.pgen.1003543