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SPO11-Independent DNA Repair Foci and Their Role in Meiotic Silencing

In mammalian meiotic prophase, the initial steps in repair of SPO11-induced DNA double-strand breaks (DSBs) are required to obtain stable homologous chromosome pairing and synapsis. The X and Y chromosomes pair and synapse only in the short pseudo-autosomal regions. The rest of the chromatin of the...

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Detalles Bibliográficos
Autores principales: Carofiglio, Fabrizia, Inagaki, Akiko, de Vries, Sandra, Wassenaar, Evelyne, Schoenmakers, Sam, Vermeulen, Christie, van Cappellen, Wiggert A., Sleddens-Linkels, Esther, Grootegoed, J. Anton, te Riele, Hein P. J., de Massy, Bernard, Baarends, Willy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675022/
https://www.ncbi.nlm.nih.gov/pubmed/23754961
http://dx.doi.org/10.1371/journal.pgen.1003538