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Mitofusin 2 Protects Hepatocyte Mitochondrial Function from Damage Induced by GCDCA

Mitochondrial impairment is hypothesized to contribute to the pathogenesis of chronic cholestatic liver diseases. Mitofusin 2 (Mfn2) regulates mitochondrial morphology and signaling and is involved in the development of numerous mitochondrial-related diseases; however, a functional role for Mfn2 in...

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Detalles Bibliográficos
Autores principales: Chen, Yongbiao, Lv, Lizhi, Jiang, Zhelong, Yang, Hejun, Li, Song, Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675030/
https://www.ncbi.nlm.nih.gov/pubmed/23755235
http://dx.doi.org/10.1371/journal.pone.0065455