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Shigella IpaH0722 E3 Ubiquitin Ligase Effector Targets TRAF2 to Inhibit PKC–NF-κB Activity in Invaded Epithelial Cells

NF-κB plays a central role in modulating innate immune responses to bacterial infections. Therefore, many bacterial pathogens deploy multiple mechanisms to counteract NF-κB activation. The invasion of and subsequent replication of Shigella within epithelial cells is recognized by various pathogen re...

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Detalles Bibliográficos
Autores principales: Ashida, Hiroshi, Nakano, Hiroyasu, Sasakawa, Chihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675035/
https://www.ncbi.nlm.nih.gov/pubmed/23754945
http://dx.doi.org/10.1371/journal.ppat.1003409