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Signal Peptide Cleavage from GP5 of PRRSV: A Minor Fraction of Molecules Retains the Decoy Epitope, a Presumed Molecular Cause for Viral Persistence

Porcine reproductive and respiratory syndrome virus (PRRSV) is the major pathogen in the pig industry. Variability of the antigens and persistence are the biggest challenges for successful control and elimination of the disease. GP5, the major glycoprotein of PRRSV, is considered an important target...

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Detalles Bibliográficos
Autores principales: Thaa, Bastian, Sinhadri, Balaji Chandrasekhar, Tielesch, Claudia, Krause, Eberhard, Veit, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675037/
https://www.ncbi.nlm.nih.gov/pubmed/23755249
http://dx.doi.org/10.1371/journal.pone.0065548