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Signal Peptide Cleavage from GP5 of PRRSV: A Minor Fraction of Molecules Retains the Decoy Epitope, a Presumed Molecular Cause for Viral Persistence
Porcine reproductive and respiratory syndrome virus (PRRSV) is the major pathogen in the pig industry. Variability of the antigens and persistence are the biggest challenges for successful control and elimination of the disease. GP5, the major glycoprotein of PRRSV, is considered an important target...
Autores principales: | Thaa, Bastian, Sinhadri, Balaji Chandrasekhar, Tielesch, Claudia, Krause, Eberhard, Veit, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675037/ https://www.ncbi.nlm.nih.gov/pubmed/23755249 http://dx.doi.org/10.1371/journal.pone.0065548 |
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