Structural analysis of the mutant protein D26G of human γS-crystallin, associated with Coppock cataract

PURPOSE: To analyze the protein structural features responsible for the aggregation properties of the mutant protein D26G human γS-crystallin (HGSC) associated with congenital Coppock-type cataract. METHODS: cDNAs of wild-type (WT) and D26G mutant HGSC were cloned and expressed in BL21 (DE3) pLysS c...

Descripción completa

Detalles Bibliográficos
Autores principales: Karri, Srinivasu, Kasetti, Ramesh Babu, Vendra, Venkata Pulla Rao, Chandani, Sushil, Balasubramanian, Dorairajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675056/
https://www.ncbi.nlm.nih.gov/pubmed/23761725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675056/
https://www.ncbi.nlm.nih.gov/pubmed/23761725

Ejemplares similares