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An Antimitotic and Antivascular Agent BPR0L075 Overcomes Multidrug Resistance and Induces Mitotic Catastrophe in Paclitaxel-Resistant Ovarian Cancer Cells

Paclitaxel plays a major role in the treatment of ovarian cancer; however, resistance to paclitaxel is frequently observed. Thus, new therapy that can overcome paclitaxel resistance will be of significant clinical importance. We evaluated antiproliferative effects of an antimitotic and antivascular...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolei, Wu, Erxi, Wu, Jun, Wang, Tian-Li, Hsieh, Hsing-Pang, Liu, Xinli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675084/
https://www.ncbi.nlm.nih.gov/pubmed/23762410
http://dx.doi.org/10.1371/journal.pone.0065686