The C-Terminal V5 Domain of Protein Kinase Cα Is Intrinsically Disordered, with Propensity to Associate with a Membrane Mimetic

The C-terminal V5 domain is one of the most variable domains in Protein Kinase C isoforms (PKCs). V5 confers isoform specificity on its parent enzyme through interactions with isoform-specific adaptor proteins and possibly through specific intra-molecular interactions with other PKC domains. The str...

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Detalles Bibliográficos
Autores principales: Yang, Yuan, Igumenova, Tatyana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675085/
https://www.ncbi.nlm.nih.gov/pubmed/23762412
http://dx.doi.org/10.1371/journal.pone.0065699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675085/
https://www.ncbi.nlm.nih.gov/pubmed/23762412
http://dx.doi.org/10.1371/journal.pone.0065699

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