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The Interaction between tRNA(Lys) (3) and the Primer Activation Signal Deciphered by NMR Spectroscopy
The initiation of reverse transcription of the human immunodeficiency virus type 1 (HIV-1) requires the opening of the three-dimensional structure of the primer tRNA(Lys) (3) for its annealing to the viral RNA at the primer binding site (PBS). Despite the fact that the result of this rearrangement i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675109/ https://www.ncbi.nlm.nih.gov/pubmed/23762248 http://dx.doi.org/10.1371/journal.pone.0064700 |