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Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens

DNA sequence variation within human leukocyte antigen (HLA) genes mediate susceptibility to a wide range of human diseases. The complex genetic structure of the major histocompatibility complex (MHC) makes it difficult, however, to collect genotyping data in large cohorts. Long-range linkage disequi...

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Detalles Bibliográficos
Autores principales: Jia, Xiaoming, Han, Buhm, Onengut-Gumuscu, Suna, Chen, Wei-Min, Concannon, Patrick J., Rich, Stephen S., Raychaudhuri, Soumya, de Bakker, Paul I.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675122/
https://www.ncbi.nlm.nih.gov/pubmed/23762245
http://dx.doi.org/10.1371/journal.pone.0064683