Leveraging Prior Information to Detect Causal Variants via Multi-Variant Regression

Although many methods are available to test sequence variants for association with complex diseases and traits, methods that specifically seek to identify causal variants are less developed. Here we develop and evaluate a Bayesian hierarchical regression method that incorporates prior information on...

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Detalles Bibliográficos
Autores principales: Long, Nanye, Dickson, Samuel P., Maia, Jessica M., Kim, Hee Shin, Zhu, Qianqian, Allen, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675126/
https://www.ncbi.nlm.nih.gov/pubmed/23762022
http://dx.doi.org/10.1371/journal.pcbi.1003093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675126/
https://www.ncbi.nlm.nih.gov/pubmed/23762022
http://dx.doi.org/10.1371/journal.pcbi.1003093

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