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Leveraging Prior Information to Detect Causal Variants via Multi-Variant Regression
Although many methods are available to test sequence variants for association with complex diseases and traits, methods that specifically seek to identify causal variants are less developed. Here we develop and evaluate a Bayesian hierarchical regression method that incorporates prior information on...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675126/ https://www.ncbi.nlm.nih.gov/pubmed/23762022 http://dx.doi.org/10.1371/journal.pcbi.1003093 |