Transition between Acute and Chronic Hepatotoxicity in Mice Is Associated with Impaired Energy Metabolism and Induction of Mitochondrial Heme Oxygenase-1

The formation of protein inclusions is frequently associated with chronic metabolic diseases. In mice, short-term intoxication with 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) leads to hepatocellular damage indicated by elevated serum liver enzyme activities, whereas only minor morphological cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Nikam, Aniket, Patankar, Jay V., Lackner, Carolin, Schöck, Elisabeth, Kratky, Dagmar, Zatloukal, Kurt, Abuja, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675145/
https://www.ncbi.nlm.nih.gov/pubmed/23762471
http://dx.doi.org/10.1371/journal.pone.0066094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675145/
https://www.ncbi.nlm.nih.gov/pubmed/23762471
http://dx.doi.org/10.1371/journal.pone.0066094

Ejemplares similares