Increased Long Chain acyl-Coa Synthetase Activity and Fatty Acid Import Is Linked to Membrane Synthesis for Development of Picornavirus Replication Organelles

All positive strand (+RNA) viruses of eukaryotes replicate their genomes in association with membranes. The mechanisms of membrane remodeling in infected cells represent attractive targets for designing future therapeutics, but our understanding of this process is very limited. Elements of autophagy...

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Detalles Bibliográficos
Autores principales: Nchoutmboube, Jules A., Viktorova, Ekaterina G., Scott, Alison J., Ford, Lauren A., Pei, Zhengtong, Watkins, Paul A., Ernst, Robert K., Belov, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675155/
https://www.ncbi.nlm.nih.gov/pubmed/23762027
http://dx.doi.org/10.1371/journal.ppat.1003401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675155/
https://www.ncbi.nlm.nih.gov/pubmed/23762027
http://dx.doi.org/10.1371/journal.ppat.1003401

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