Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol

Inflammasome activation is important for antimicrobial defense because it induces cell death and regulates the secretion of IL-1 family cytokines, which play a critical role in inflammatory responses. The inflammasome activates caspase-1 to process and secrete IL-1β. However, the mechanisms governin...

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Detalles Bibliográficos
Autores principales: Casson, Cierra N., Copenhaver, Alan M., Zwack, Erin E., Nguyen, Hieu T., Strowig, Till, Javdan, Bahar, Bradley, William P., Fung, Thomas C., Flavell, Richard A., Brodsky, Igor E., Shin, Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675167/
https://www.ncbi.nlm.nih.gov/pubmed/23762026
http://dx.doi.org/10.1371/journal.ppat.1003400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675167/
https://www.ncbi.nlm.nih.gov/pubmed/23762026
http://dx.doi.org/10.1371/journal.ppat.1003400

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