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Carriers of a novel frame-shift insertion in WNT16a possess elevated pancreatic expression of TCF7L2

BACKGROUND: The discovery of TCF7L2 as a global type 2 diabetes (T2D) gene has sparked investigations to explore the clinical utility of its variants for guiding the development of new diagnostic and therapeutic strategies. However, interpreting the resulting associations into function still remains...

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Detalles Bibliográficos
Autores principales: Howard, Eric W, Been, Latonya F, Lerner, Megan, Brackett, Daniel, Lightfoot, Stan, Bullen, Elizabeth C, Sanghera, Dharambir K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675375/
https://www.ncbi.nlm.nih.gov/pubmed/23617586
http://dx.doi.org/10.1186/1471-2156-14-28