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Different actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1

BACKGROUND: Chemokines are involved in many pathological responses of the brain. Astrocytes produce various chemokines in brain disorders, but little is known about the factors that regulate astrocytic chemokine production. Endothelins (ETs) have been shown to regulate astrocytic functions through E...

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Detalles Bibliográficos
Autores principales: Koyama, Yutaka, Kotani, Mao, Sawamura, Tadateru, Kuribayashi, Miho, Konishi, Rika, Michinaga, Shotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675376/
https://www.ncbi.nlm.nih.gov/pubmed/23627909
http://dx.doi.org/10.1186/1742-2094-10-51