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Increased expression of pigment epithelium-derived factor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injury(‡)

AIMS: Mesenchymal stem cells (MSCs) can ameliorate myocardial infarction (MI) injury. However, older-donor MSCs seem less efficacious than those from younger donors, and the contributing underlying mechanisms remain unknown. Here, we determine how age-related expression of pigment epithelium-derived...

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Detalles Bibliográficos
Autores principales: Liang, Hongliang, Hou, Huiyuan, Yi, Wei, Yang, Guodong, Gu, Chunhu, Lau, Wayne Bond, Gao, Erhe, Ma, Xinliang, Lu, Zifan, Wei, Xufeng, Pei, Jianming, Yi, Dinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675387/
https://www.ncbi.nlm.nih.gov/pubmed/21606086
http://dx.doi.org/10.1093/eurheartj/ehr131