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miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation

AIMS: The long-term failure of autologous saphenous vein bypass grafts due to neointimal thickening is a major clinical burden. Identifying novel strategies to prevent neointimal thickening is important. Thus, this study aimed to identify microRNAs (miRNAs) that are dysregulated during neointimal fo...

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Detalles Bibliográficos
Autores principales: McDonald, Robert A., White, Katie M., Wu, Junxi, Cooley, Brian C., Robertson, Keith E., Halliday, Crawford A., McClure, John D., Francis, Sheila, Lu, Ruifaug, Kennedy, Simon, George, Sarah J., Wan, Song, van Rooij, Eva, Baker, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675389/
https://www.ncbi.nlm.nih.gov/pubmed/23530023
http://dx.doi.org/10.1093/eurheartj/eht105