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Structure and mechanism of the 2′,3′ phosphatase component of the bacterial Pnkp-Hen1 RNA repair system
Pnkp is the end-healing and end-sealing component of an RNA repair system present in diverse bacteria from many phyla. Pnkp is composed of three catalytic modules: an N-terminal polynucleotide 5′ kinase, a central 2′,3′ phosphatase and a C-terminal ligase. The phosphatase module is a Mn(2+)-dependen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675462/ https://www.ncbi.nlm.nih.gov/pubmed/23595150 http://dx.doi.org/10.1093/nar/gkt221 |