Laser capture microdissection–reduced representation bisulfite sequencing (LCM-RRBS) maps changes in DNA methylation associated with gonadectomy-induced adrenocortical neoplasia in the mouse

DNA methylation is a mechanism for long-term transcriptional regulation and is required for normal cellular differentiation. Failure to properly establish or maintain DNA methylation patterns leads to cell dysfunction and diseases such as cancer. Identifying DNA methylation signatures in complex tis...

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Detalles Bibliográficos
Autores principales: Schillebeeckx, Maximiliaan, Schrade, Anja, Löbs, Ann-Kathrin, Pihlajoki, Marjut, Wilson, David B., Mitra, Robi D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675465/
https://www.ncbi.nlm.nih.gov/pubmed/23589626
http://dx.doi.org/10.1093/nar/gkt230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675465/
https://www.ncbi.nlm.nih.gov/pubmed/23589626
http://dx.doi.org/10.1093/nar/gkt230

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