Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver

Aberrant DNA methylation is a common feature of neoplastic lesions, and early detection of such changes may provide powerful mechanistic insights and biomarkers for carcinogenesis. Here, we investigate dynamic changes in the mouse liver DNA methylome associated with short (1 day) and prolonged (7, 2...

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Detalles Bibliográficos
Autores principales: Thomson, John P., Hunter, Jennifer M., Lempiäinen, Harri, Müller, Arne, Terranova, Rémi, Moggs, Jonathan G., Meehan, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675467/
https://www.ncbi.nlm.nih.gov/pubmed/23598998
http://dx.doi.org/10.1093/nar/gkt232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675467/
https://www.ncbi.nlm.nih.gov/pubmed/23598998
http://dx.doi.org/10.1093/nar/gkt232

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