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Sequence features of yeast and human core promoters that are predictive of maximal promoter activity

The core promoter is the region in which RNA polymerase II is recruited to the DNA and acts to initiate transcription, but the extent to which the core promoter sequence determines promoter activity levels is largely unknown. Here, we identified several base content and k-mer sequence features of th...

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Detalles Bibliográficos
Autores principales: Lubliner, Shai, Keren, Leeat, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675475/
https://www.ncbi.nlm.nih.gov/pubmed/23599004
http://dx.doi.org/10.1093/nar/gkt256