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Sequence features of yeast and human core promoters that are predictive of maximal promoter activity
The core promoter is the region in which RNA polymerase II is recruited to the DNA and acts to initiate transcription, but the extent to which the core promoter sequence determines promoter activity levels is largely unknown. Here, we identified several base content and k-mer sequence features of th...
Autores principales: | Lubliner, Shai, Keren, Leeat, Segal, Eran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675475/ https://www.ncbi.nlm.nih.gov/pubmed/23599004 http://dx.doi.org/10.1093/nar/gkt256 |
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