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Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization

All orthobunyaviruses possess three genome segments of single-stranded negative sense RNA that are encapsidated with the virus-encoded nucleocapsid (N) protein to form a ribonucleoprotein (RNP) complex, which is uncharacterized at high resolution. We report the crystal structure of both the Bunyamwe...

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Detalles Bibliográficos
Autores principales: Ariza, Antonio, Tanner, Sian J., Walter, Cheryl T., Dent, Kyle C., Shepherd, Dale A., Wu, Weining, Matthews, Susan V., Hiscox, Julian A., Green, Todd J., Luo, Ming, Elliott, Richard M., Fooks, Anthony R., Ashcroft, Alison E., Stonehouse, Nicola J., Ranson, Neil A., Barr, John N., Edwards, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675483/
https://www.ncbi.nlm.nih.gov/pubmed/23595147
http://dx.doi.org/10.1093/nar/gkt268