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Din7 and Mhr1 expression levels regulate double-strand-break–induced replication and recombination of mtDNA at ori5 in yeast

The Ntg1 and Mhr1 proteins initiate rolling-circle mitochondrial (mt) DNA replication to achieve homoplasmy, and they also induce homologous recombination to maintain mitochondrial genome integrity. Although replication and recombination profoundly influence mitochondrial inheritance, the regulatory...

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Detalles Bibliográficos
Autores principales: Ling, Feng, Hori, Akiko, Yoshitani, Ayako, Niu, Rong, Yoshida, Minoru, Shibata, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675488/
https://www.ncbi.nlm.nih.gov/pubmed/23598996
http://dx.doi.org/10.1093/nar/gkt273