Fingolimod—A Sphingosine-Like Molecule Inhibits Vesicle Mobility and Secretion in Astrocytes

In the brain, astrocytes signal to the neighboring cells by the release of chemical messengers (gliotransmitters) via regulated exocytosis. Recent studies uncovered a potential role of signaling lipids in modulation of exocytosis. Hence, we investigated whether sphingosine and the structural analog...

Descripción completa

Detalles Bibliográficos
Autores principales: Trkov, Saša, Stenovec, Matjaž, Kreft, Marko, Potokar, Maja, Parpura, Vladimir, Davletov, Bazbek, Zorec, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675637/
https://www.ncbi.nlm.nih.gov/pubmed/22639011
http://dx.doi.org/10.1002/glia.22361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675637/
https://www.ncbi.nlm.nih.gov/pubmed/22639011
http://dx.doi.org/10.1002/glia.22361

Ejemplares similares