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Fingolimod—A Sphingosine-Like Molecule Inhibits Vesicle Mobility and Secretion in Astrocytes
In the brain, astrocytes signal to the neighboring cells by the release of chemical messengers (gliotransmitters) via regulated exocytosis. Recent studies uncovered a potential role of signaling lipids in modulation of exocytosis. Hence, we investigated whether sphingosine and the structural analog...
Autores principales: | Trkov, Saša, Stenovec, Matjaž, Kreft, Marko, Potokar, Maja, Parpura, Vladimir, Davletov, Bazbek, Zorec, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675637/ https://www.ncbi.nlm.nih.gov/pubmed/22639011 http://dx.doi.org/10.1002/glia.22361 |
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