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Leukocyte and serum S100A8/S100A9 expression reflects disease activity in ANCA-associated vasculitis and glomerulonephritis

Antineutrophil cytoplasm antibody (ANCA)–associated vasculitis (AAV) commonly results in glomerulonephritis, in which neutrophils and monocytes have important roles. The heterodimer calprotectin (S100A8/S100A9, mrp8/14) is a Toll-like receptor-4 ligand found in neutrophils and monocytes and is eleva...

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Detalles Bibliográficos
Autores principales: Pepper, Ruth J, Hamour, Sally, Chavele, Konstantia-Maria, Todd, Sarah K, Rasmussen, Niels, Flint, Shaun, Lyons, Paul A, Smith, Kenneth G C, Pusey, Charles D, Cook, H Terence, Salama, Alan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675710/
https://www.ncbi.nlm.nih.gov/pubmed/23423260
http://dx.doi.org/10.1038/ki.2013.2